Alitame is an intense sweetener, with sweetness potency 2000 times greater than that of sucrose. Alitame is prepared by a multistep synthesis involving the reaction between two intermediates, (S)-[2,5-dioxo-(4-thiazolidine)] acetic acid and (R)-2-amino-N-(2,2,4,4-tetramethyl-3-thietanyl) propanamide.

The final product is isolated and purified through crystallization of an alitame-4-methylbenzenesulfonic acid molecules, followed by additional purification steps, and finally recrystallization from water.

Chemical Structure and Properties

Alitame is a dipeptide of L-aspartic acid and D-alanine, with a terminal N-substituted tetramethylthietanyl-amine moiety.

Functionality in Food

Alitame is used as an intensive sweetener.


Alitame is used in a wide range of foods and beverages, including bakery wares, water-based flavored drinks, dairy-based drinks, dairy-based desserts, cream, edible ices, jams, confectionery and some dietetic foods.




Alitame is not allowed in every country.

Click here to find suppliers of alitame.

To read more about alitame: wikipedia


Ria Van Hoef

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